Adjunctive hyperbaric oxygen therapy in the treatment of atrophic tibial nonunion with ılizarov external fixator: a radiographic and scintigraphic study in rabbits.Kurklu M1, Yurttaş Y, Kose O, Demiralp B, Yuksel HY, Komurcu M.
[h=3]Acta Orthop Traumatol Turc. 2012;46(2):126-31.[/h][h=3]Abstract[/h]OBJECTIVE:
The aim of this experimental study was to determine the effects of adjunctive hyperbaric oxygen therapy (HBO) on atrophic tibial nonunion treatment using Ilizarov external fixator.
METHODS:
Twenty New Zealand white rabbits were randomly divided into two equal groups. A circular external fixator was applied to the right tibia of all the rabbits. A 5-mm bone block was resected and a tibial pseudarthrosis was obtained after a 6-month waiting period. The experimental group rabbits (n=10) underwent daily 2.5 ATA HBO therapy for 2 hours for 20 days and the control group rabbits (n=10) did not receive any corresponding treatment. Osteoblastic activity was evaluated with bone scintigraphy on days 30 and 90. Fracture healing was evaluated by plain radiographs on days 30 and 90.
RESULTS:
On Day 30, radiological scores were statistically similar in both groups (p=0.167). However, on Day 90, the experimental group displayed significantly higher radiological scores (p